L’ivermectine (Stromectol) est un antiparasitaire dont l’action repose sur la liaison sélective aux canaux chlore activés par le glutamate présents dans les cellules nerveuses et musculaires des parasites. Cette fixation entraîne une augmentation du flux de chlore, provoquant une hyperpolarisation et une paralysie irréversible. L’ivermectine est active contre la gale, l’onchocercose et certaines strongyloïdoses. Sa biodisponibilité orale est variable, augmentée par la prise alimentaire, et son élimination est principalement fécale via un métabolisme hépatique. Elle ne traverse pas la barrière hémato-encéphalique, ce qui limite les effets neurologiques chez l’homme. Les précautions concernent l’interaction avec les inhibiteurs du CYP3A4, ainsi que les réactions inflammatoires dues à la destruction massive des parasites. Dans les documents de référence, stromectol prix est associé à des protocoles précis adaptés aux différentes infestations, avec une attention particulière sur la sécurité d’emploi en cas d’immunodépression.

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March 2007
NEW DRUG TERMS
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CONTINUING EDUCATION ARTICLES
Article Number 569934: Anonymous. Telbivudine (Tyzeka) for Chronic Hepatitis B. (IDIS Note: The
1.0 Hour of CE Credit is for All Articles in the Issue, Article Numbers 569933-569934). Med Lett Drugs
Ther 2007, 49:11-12. (0.1 CEU)
Article Number 569933: Anonymous. Pioglitazone/Glimepiride (Duetact) for Diabetes. (IDIS Note: The
1.0 Hour of CE Credit is for All Articles in the Issue, Article Numbers 569933-569934). Med Lett Drugs
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Article Number 569882: Fleming WK. AHRQ's Effective Health Care Program: Its Impact on Managed
Care (IDIS Note: The 2.5 Hours of CE Credit is for All Articles in the Issue, Article Numbers 569880-
569882). J Manag Care Pharm 2007, 13:S19-S20. (0.25 CEU)
Article Number 569881: Solomon DH. The Comparative Safety and Effectiveness of TNF-Alpha Antag-
onists in Adult Rheumatoid Arthritis Study by AHRQ Effective Health Care Program. (IDIS Note: The 2.5
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Article Number 569880: Chao SH, Urbano FL. Medicare Section 1013 and AHRQ's Effective Health
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569880-569882). J Manag Care Pharm 2007, 13:S3-S6. (0.25 CEU)
Article Number 569843: Kerr JL, Timpe EM, Karpinski JP. Varenicline: A Novel Nicotinic Receptor Par-
tial Agonist for Smoking Cessation. J Pharm Technology 2007, 23:23-29. (0.1 CEU)
Article Number 569793: Anonymous. Angeliq for Treatment of Menopausal Symptoms. Med Lett Drugs
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Article Number 569480: Reeder CE. Anemia in Cancer and Critical Care Patients: Pharmacoeconomic
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Article Number 569222: Cada DJ, Levien T, Baker DE. Posaconazole Oral Suspension. Hosp Pharm
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Article Number 568817: Kretsinger K, Broder KR, Cortese MM, Joyce MP, et al. Preventing Tetanus,
Diphtheria, and Pertussis Among Adults: Use of Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular
Pertussis Vaccine: Recommendations of Advisory Committee on Immunization Practices.MMWR 2006,
55:1-37. (0.25 CEU)
FDA Advisory Committee Meetings
Article Numbers: 568547-568550: Pulmonary-Allergy Drugs Advisory Committee Meeting, July 14,
2005. FDA Advsiory Commttee 2005
Article Numbers: 568540-568546: Psychopharmacologic Drugs Advisory Committee Meeting, De-
cember 2, 2005. FDA Advisory Committee 2005.
Article Numbers: 568535-568539: Psychopharmacologic Drugs Advisory Committee Meeting, Oc-
tober 25, 2005. FDA Advisory Committee 2005.
Article Numbers: 568529-568534: Pulmonary-Allergy Drugs Advisory Committee Meeting, June 6,
2005. FDA Advisory Committee 2005.
Article Numbers: 568524-568528: Psychopharmacologic Drugs Advisory Committee Meeting, Oc-
tober 26, 2005, FDA Advisory Committee 2005.
Article Numbers: 568519-568523: Pulmonary-Allergy Drugs Advisory Committee Meeting, July 13,
2005. FDA Advisory Committee 2005.

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