Missouricancer.com

BREAST STUDIES
USON 10-195 "Call Project Manager"
A Phase 1/2 Dose-Escalation Study of XL147 or XL765 in Combination with Letrozole in subjects with Hormone "Arm 1 opened 02/16/12"
Receptor-Positive and HER2-Negative Breast Cancer refractory to a Nonsteroidal Aromatase Inhibitor (XL147-202).
Locally Recurrent/Metastatic
USON 11-086
A Phase 3 Open-Label, Randomized, Multicenter Study Of NKTR-102 Versus Treatment Of Physician's ChoiceTPC) In Patients With Locally Recurrent Or Metastatic Breast Cancer Previously Treated With An Anthracycline, A Taxane, And Capecitabine (The BEACON Study) Metastatic 1/2/3 Line
USON 09-097 Post Trastuzumab
A randomized, Phase III, Open-label study of Lapatinib plus Trastuzumab versus Trastuzumab as continued HER2 suppression therapy after completion of 1st/2nd line Trastuzumab plus chemo in subjects with HER2 Positive Metastatic BC.
Neo-Adjuvant
USON 10-121
Prediction of Response to Neoadjuvant Chemotherapy in Women with Operable Breast Cancer (PT-304) COLON STUDIES
Metastatic 2nd Line
USON 10-101 "Enrollment On Hold"
Randomized, Double-blind, Multicenter Phase III study of Irinotecan, Folinic Acid, and 5-Fluorouracil (FOLFIRI) PlusRamucirumab or Placebo in patients with Metastatic Colorectal Carcinoma Progressive During or Following 1st- line combotherapy with Bevacizumab, Oxaliplatin and a Fluoropyrimidine. LUNG: NSCLC
Advanced First Line Therapy
USON 08-035
A randomized, double blinded, Placebo-controlled study to evaluate the long-term safety and efficacy of Darbepoetin Alfain anemic subjects with advanced stage Non-Small Lung Cancer receiving multi-cycle chemotherapy.
An Open-label, Multicenter, Randomized, Phase II study of a Recombinant Human Anti-VEGFR-2 Monoclonal Antibody,
IMC-1121B in combination with Platinum-based chemotherapy versus Platinum-based Chemotherapy alone as first-line
treatment of patients with recurrent or advanced NSCLC. "Open to Patients with SQUAMOUS histology only"
Second Line Therapy
USON 10-061 "Enrollment On Hold"
Protocol I4T-MC-JVBA (also known as IMCL CP12-1027) A Randomized, Double-Blind, Phase 3 Study of Docetaxel and Ramucirumab versus Docetaxel and Placebo in the Treatment of Stage IV Non-Small Cell Lung Cancer Following Disease Progression after One Prior Platinum- Based Therapy. LYMPHOMA
First Line Therapy
An open-label, Randomized, Phase 2 Study to Assess the Effectiveness of RCHOP With or Without VELCADE in previously untreated patients with Non-Germinal Center B-Cell-like diffuse Large B-Cell Lymphoma.
FOLLICULAR LYMPHOMA
GSK OMB113676
Study comparing a new drug (Ofatumumab) to treat Follicular Lymphoma with an approved drug (Rituximab).
LYMPHOMA (NON-HODGKINS)
Relapsed
USON 10215
A Randomized Multicenter Study Comparing Pixantrone + Rituximab with Gemcitabine + Rituximab in Patients with Aggressive B-cell Non-Hodgkin Lymphoma Who Have Relapsed after Therapy with CHOP-R or an Equivalent Regimen and are Ineligible for Stem Cell Transplant MYELODYSPLASTIC SYNDROME
USON 09152
A multi-center, randomized, double-blind, placebo-controlled clinical trial of deferasirox in patients with MS(low/int-1 risk) and transfusional iron overload (TELESTO) Protocol Number: CICL670A2302.
ORAL CHEMO DELAY PROTOCOL
MCA 2011A
Evaluation of Delays in Instituting Oral Chemotherapy

Source: http://missouricancer.com/files/2009/04/MCA_Open_Protocols15.pdf