Medicalexaminer.cuyahogacounty.us
Office of the Cuyahoga County Medical Examiner's Office
11001 Cedar Avenue, Cleveland, Ohio 44106
DRUGS ANALYZED/QUANTIFIED BY CCRFSL/CCMEO TOXICOLOGY
VOLATILES: Acetaldehyde, Acetone, Acetonitrile*, Butane, Chloroform*, Dichloromethane*, Ethanol, Ethyl Acetate*, Formaldehyde, Isopropanol, Methane,
Methanol, Paraldehyde*, Propane, Toluene*.
ETHANOL, ACETONE, ISOPROPANOL, and
METHANOL CONFIRMATION(s) by alternative GC column a nd/or
alternative specimens. METHANOL is differentiated from
FORMALDEHYDE by Colorimetry (Qualitative).
Sedatives, Hypnotics, Anti-Epileptic and Other Acidic/Neutral Drugs:
Amobarbital, Butalbital, Caffeine, Carbamazepine, Carisoprodol, Glutethimide, Ibuprofen, Levetiracetam, Mephenytoin, Meprobamate, Metaxalone, Naproxen, Pentobarbital, Pentoxifylline, Phenobarbital, Phenytoin, Primidone, Secobarbital, Theophylline, Topiramate;
ACIDIC NEUTRALs Screened and Quantified by GC-FID and Confirmed by GC/MS.
CARBON MONOXIDE* (Carboxyhemoglobin)
by CO-Oximetry: Carbon Monoxide, Methemoglobin, Hemoglobin
; CARBON MONOXIDE CONFIRMATION by Spectrophotometry and/or
Microdiffusion.
GLYCOLS*: Ethylene Glycol, Propylene Glycol S
creened and Confirmed by GC/MS.
CYANIDE*: Screened and Quantified by Colorimetry.
EMIT
SCREEN: SYMPATHOMIMETIC AMINES (SMAs) (target = d-Amphetamine);
BENZODIAZEPINES (Target= Oxazepam);
COCAINE (Target= Benzoylecgonine (a cocaine metabolite);
CANNABINOIDS (Target= 11-nor--9-THC-COOH (a marijuana metabolite);
OPIATES (Target= Morphine);
PHENCYCLIDINE (Target= Phencyclidine).
7)
ELISA (
E nzyme-
L inked
I mmuno
S orbent
A ssay)
SCREEN :
SMAs (Target = d-Amphetamine);
Barbiturates (Target = Pentobarbital);
Benzodiazepines (Target =
Alprazolam);
Cannabinoids (Target = 11-nor--9-THC-COOH (a marijuana metabolite);
Carisoprodol (Target = Carisoprodol);
Cocaine Metabolite (Target =
Benzoylecgonine);
Fentanyl (Target = Fentanyl);
Methamphetamine (Target = d-Methamphetamine);
Oxycodone (Target = Oxycodone);
Phencyclidine (Target =
Phencyclidine);
Tricyclic Antidepressants (Target = Nortriptyline);
Methadone (Target = Methadone);
Opiates (Target = Morphine).
BASIC DRUGS by GC/MS (Quantitation and Confirmation): Amantadine, Amitriptyline, Amoxapine, Amphetamine, Atropine, Benztropine, Brompheniramine,
Bupivacaine, Bupropion, Bupropion Metabolites, Buspirone, Caffeine, Carbinoxamine, Chlorophenylpiperazine, Chlorpheniramine, Chlorpromazine, Citalopram,
Clomipramine, Clozapine, Cocaethylene, Cocaine, Codeine, Cocaine and metabolites, Cotinine, Cyclizine, Cyclobenzaprine, Desalkylflurazepam, Desipramine, Desmethyl
Chlordiazepoxide, Desmethyl Clomipramine, Desmethyl Clozapine, Desmethylsertraline, Desmethylvenlafaxine, Dextromethorphan, Diazepam, Diethylpropion,
Diphenhydramine, Disopyramide, Diltiazem, Doxepin, Doxylamine, Ecgonine methyl ester, Ephedrine/Pseudoephedrine, Fenfluramine, Fentanyl, Fluoxetine,
Fluvoxamine, Guaifenesin, Haloperidol, Hydrocodone, Hydroxyzine, Imipramine, Ketamine, Laudanosine, Lidocaine, Lidocaine mb (MEGX), Loxapine, Maprotiline,
Meclizine, Meperidine, Mephentermine, Mesoridazine, Methadone, Methadone primary mb (EDDP), Methadone secondary mb (EMDP), Methamphetamine, Methylene-
dioxyamphetamine (MDA), Methylenedioxymethamphetamine (MDMA), Methylenedioxypyrovalerone (MDPV), Methylphenidate, Metoprolol, Mexiletine, Midazolam,
Mirtazapine, Nefazodone, Nicotine, Nordiazepam, Nordoxepin, Norfluoxetine, Normeperidine, Norpropoxyphene, Nortriptyline, Norverapamil, Olanzapine, Orphenadrine,
Oxycodone, Papaverine, Paroxetine, Pentazocine, Pentoxifylline, Perphenazine, Phencyclidine, beta-Phenethylamine, Pheniramine, Phendimetrazine, Phenmetrazine,
Phentermine, Phenylpropanolamine, Phenytoloxamine, Procaine, Promethazine, Propoxyphene, Propranolol, Protriptyline, Pseudoehedrine, Pyrilamine, Quetiapine,
Quinidine, Quinine, Sertraline, Thioridazine, Tramadol, Tranylcypromine, Trazodone, Trihexylphenidyl, Trimipramine, Venlafaxine, Verapamil, Zolpidem.
ACETAMINOPHEN SCREEN: Acetaminophen
by Colorimetry (Qualitative).
SALICYLATE SCREEN: Salicylate (Aspirin
) by Colorimetry (Qualitative) ,
SALICYLATE CONFIRMATION by Gas Chromatography .
XANTHINES by GC/MS: Acetaminophen, Caffeine.
CLINICAL CHEMISTRIES (CHEM7): Ketones, pH, Specific Gravity, and Electrolytes (Sodium, Potassium, Chloride, TCO2, Glucose, Urea, Creatinine).
13) COCAINE CONFIRMATION by GC/MS: Anhydroecgonine methyl ester, Benzoylecgonine, Cocaine, Cocaethylene, Ecgonine ethyl ester*, Ecgonine methyl ester.
CANNABINOIDS by GC/MS: Cannabinoids (ng/mL; mcg/L): D9-THC, 11-OH-D9-THC (a marijuana metabolite), 11-nor- D9-THC-COOH (a marijuana metabolite),
TOTAL11-nor- D9-THC-COOH (a marijuana metabolite).
OPIATES by GC/MS (ng/mL)
: Morphine, 6-Acetylmorphine (heroin metabolite), Codeine, Hydrocodone, Dihydrocodeine, Hydromorphone, Norcodeine*, Oxycodone;
Oxymorphone.
TOTAL OPIATES by GC/MS-Hydrolysis followed by OPIATES by GC/MS .
BENZODIAZEPINE CONFIRMATION by GC/MS: Alprazolam/ metabolite, Diazepam/ metabolites, Clonazepam, Lorazepam, Midazolam/metabolite, Triazolam.
17) SYMPATHOMIMETIC AMINES CONFIRMATION by GC/MS analysis (ng/mL)
: Amantadine, Amphetamine, beta-Phenethylamine, MDEA, Methamphetamine,
Methylenedioxyamphetamine (MDA), Methylenedioxymethamphetamine (MDMA), Phentermine, Phenylpropanolamine, Pseudoephedrine.
GHB by GC/MS (mg/L)
: Gamma-hydroxybutyric acid (gamma hydroxybutyrate).
FENTANYL by GC/MS (ng/mL)
: Fentanyl, Sufentanil, Alfentanil.
20) SENT OUT TO REFERENCE LABS: Synthetic Cannabinoids and Synthetic Cathinones, Epinephrine, 7-amino Flunitrazepam, Flunitrazepam, IgE, Insulin, LSD,
Nefedipine, C-Peptide, Psilocin, Risperidone, Tryptase, Warfarin, Valproic Acid,
HEAVY METAL SCREEN: (Antimony, Arsenic, Lead, Barium, Cadmium, Bismuth,
Mercury, Selenium) or any other drugs not listed above.
*BY REQUEST ONLY; ABBREVIATIONS: POS=Positive; NEG=Negative; UNS=Specimen unsuitable for testing; NTDN=Not Done; QNS=Quantity insufficient for
analysis; CHEM7=Clinical Chemistry; < =less than; > =greater than; LRL= Lower reporting limit; C.L. = Confidence Level.
UNITS FOR VOLATILES: 100 mg/dL≡ 0.100 g/dL ≡ 0.100 g/%.
UNITS: 1 mg/L = 1000 µg/L = 1000 ng/mL.
Notification of Customers of Toxicology Capabilities
Source: http://medicalexaminer.cuyahogacounty.us/pdf_medicalexaminer/en-US/NotificationCustomersToxCapabilities.pdf
CHAPTER 55 EXPERIMENTAL AIRCRAFT ASSOCIATION APRIL 2010 Meetings are the 2nd Saturday of each Month EAA Chapter 55 Hangar - Mason Jewett Airport – 643 Aviation Drive, Mason, MI 48854 Pres: Ken Vandenbelt 589-5051 Vice Pres: Bill Purosky 214-2729 Treas: Al Spalding 676-3370 Secr: Vickie Vandenbelt 589-5051 Editor: Warren Miller 214-2656 (all Area Code 517 ) www.EAA55.org
February 2005 Vol. 2 No. 2 increased ability to produce nitric oxide, which What’s In the News relaxes the artery and improves endothelialfunction. Folic acid also lowers homocysteineThis month I’d like to share with you some of thelevels in the blood stream, which can directlymost recent articles that have come out in thedamage the endothelial lining of arteries. medical journals
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