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Basic Respiratory Pharmacology (RSPT 1113)
Credit: 1 semester credit hours (1 hour lecture, 1 hour lab)
Prerequisite: RSPT 1201
Co-requisite: RSPT 1329, RSPT 1207, RSPT 2310, RSPT 1325
Course Description:
A study of basic pharmacological principles/practices of respiratory care drugs.
Emphasis on classification, routes of administration, dosages/calculations, and
physiological interaction.
Required Textbook and Materials
1. Egan’s Fundamentals of Respiratory Care ( ISBN # 978-0-323-03657-3) 2. Egan’s Fundamentals of Respiratory Care Workbook (ISBN # 978-0-323-05188- 3. Integrated Cardiopulmonary Pharmacology- by Colbert and Mason- second Assessing Response to Bronchodilator Therapy at point of care Selection of Device for Delivery of aerosol to the Lung Parencheyma 5. A package of #882 Scantrons and #2 pencils Course Objectives
Upon completion of this course the student will be able to: Explain the mode of action,
clinical indications, dosages, hazards, and side effects of respiratory care drugs; calculate
drug dosages; and select optimal drugs used in the practice of respiratory care.
The student will be able to:
1. Select appropriate medication and dosage to produce a desired patient outcome (SCANS: F3,F8,F9,C1,C5,C11,C16,C18,C19,C20) 2. Identify indications/ hazards/side effects for various cardiopulmonary medication 3. Calculate proper drug dosage for various cardiopulmonary medications 4. Identify/select/modify delivery device for various cardiopulmonary medications RSPT 1113
Course Syllabi
Spring 2010
SCANS Skills and Competencies
Beginning in the late 1980’s, the U.S. Department of Labor Secretary’s Commission on
Achieving Necessary Skills (SCANS) conducted extensive research and interviews with
business owners, union leaders, supervisors, and laborers in a wide variety of work
settings to determine what knowledge workers needed in order to perform well on a job.
In 1991 the Commission announced its findings in What Work Requires in Schools. In its
research, the Commission determined that “workplace know-how” consists of two
elements: foundation skills and workplace competencies. The three-part foundation
skills and five-part workplace competences are further defined in the SCANS attachment
Course Outline
RSPT 1113
Course Syllabi
Spring 2010
Grade Scale
RSPT 1113
Course Syllabi
Spring 2010
Course Evaluation
Final grades will be calculated according to the following criteria: Course Requirements
1. Egan workbook Chapter 32- Airway Pharmacology Course Policies
1. No food or drink, or use of tobacco products in class 2. Beepers, telephones, headphones, and other electronic devices must be turned off 6. Abide by policies within the Respiratory Care Handbook 7. Abide by instructor specific policies; this will be distributed on the first class day. 8. Exam dates will be distributed the first class day. Disabilities Statement
The Americans with Disabilities Act of 1992 and Section 504 of the Rehabilitation Act of 1973 are federal anti-discrimination statutes that provide comprehensive civil rights for persons with disabilities. Among other things, these statutes require that all students with documented disabilities be guaranteed a learning environment that provides for reasonable accommodations for their disabilities. If you believe you have a disability requiring an accommodation, please contact the Special Populations Coordinator at (409) 880-1737 or visit the office in Student Services, Cecil Beeson Building. Course Schedule
Week Topic
Required Reading
Pharmacology- Chapter 1, Egan page 668-669 Integrated Cardiopulmonary Pharmacology- Chapter 3 RSPT 1113
Course Syllabi
Spring 2010
Week Topic
Required Reading
Pharmacology- Chapter 5, Egan page 670- 676 Integrated Cardiopulmonary Pharmacology- Chapter 5 Integrated Cardiopulmonary Pharmacology-Chapter 5 Exam #2/Chapter 6- Mucokinetics and Integrated Cardiopulmonary surfactants Pharmacology- Chapter 6 , Egan page 677-680 Pharmacology- Chapter 6&7- Egan page 680-685 Integrated Cardiopulmonary Pharmacology- Chapter 7 Chapter 7- AntiInflammatory/ Chapter Integrated Cardiopulmonary 8 Anti-infective agents Pharmacology- Chapter 8- Egan page 685-689 Integrated Cardiopulmonary Pharmacology- Chapter 8 Integrated Cardiopulmonary Pharmacology- Chapter 9 and 10 Integrated Cardiopulmonary Pharmacology- Chapter 12 , Egan page 690-691 Exact exam dates will be distributed on the first class day. This scheduled may be adjusted to facilitate student learning. RSPT 1113
Course Syllabi
Spring 2010
Specific Objectives:
Pharmacologic Principles
Upon completion of this course the student will be able to:
1. Use drug references as a source of information 2. Discuss/identify advantage and disadvantages of different routes of administration 3. Identify abbreviations used in drug administration routes. ( ie: PO, IV, SL,NG, 4. Define/ identify the following : drug absorption, distribution, metabolism, and 5. Discuss/ identify factors that myay alter a patients response to drug therapy 6. Discuss/ identify poisioning, adverse drug reactions and interactions 7. Discuss/ identify responsibilities of drug administration 8. Identify components of a medication order 9. Identify common abbreviations used with medication delivery 10. Identify/discuss the five rights of medication administration 11. Discuss/ identify half-life, loading dose, maintaince dose 12. Define toxicology, emetics 13. Discuss drug tolerance, desentization and dependence 14. Define/ identify the term agonistis and antagonists Metric system and drug dosage calculations
Upon completion of this course the student will be able to:
1. Perform conversions of units of measure within the metric system 2. Perform drug dosage calculations ( % solution, dose on hand related to desired dose, solution strengths in ratio forms, drug orders in drops) The Pharmacology of the Autonomic Nervous System
Upon completion of this course the student will be able to:
1. Describe/identify the divisions of the central and peripheral nervous system 2. Describe/identify the neurotransmitters and receptor of the ANS( alpha, beta 1 3. State/identify four classifications of the ANS 4. Describe/identify the effects of the parasympathetic and sympathetic nervous systems on the heart, lungs, eyes, gastointestional systems. Bronchodilators
Upon completion of this course the student will be able to:
1. Describe/ identify the neurologic control of bronchial smooth muscle, including the sympathetic and parasympathetic nerves, their chemical mediators and how bronchodilation is achieved 2. State/identify the mechanism of bronchoconstriction 3. Describe/define the following sympathmimetic,sympathelytic, 4. Summarizes the effects each (sympathmimetic,sympathelytic, parasympathmimetic, parasympathlytic )have on Bronchial smooth muscle, Mucus secretion, heart rate, blood pressure, pupils, blood glucose and insulin. 5. State /identify three divisions of bronchodilators 6. List the mechanisms of mast degranulation RSPT 1113
Course Syllabi
Spring 2010
7. State/identify how the following sympathomimetic (β-adrenergics) agents work, their indications, drug dosages and hazards, generic and trade names of each. (Epinephrine, racemic epinephrine, isoproterenol, isoetharine, biolterol, metaproterenol, terbutaline, albuterol, levalbuterol, pirbuterol, salmeterol, 8. State/identify how the following anticholinergics (parasympaatholytics) agents work, their indications, drug dosages and hazards, generic and trade names of each. (Ipratropium bromide, tiotropium bromide) 9. State/identify how the Xanthines (methylxantines) agents work, their indications, hazards (side effects), therapeutic levels 10. Identify common Xanthine trade names (elixophyllin, slo-phyllin, slo-bid, theolair, theo-dur, theobid, respbid, sustaire) The Mucokinetic and Surfactants
Upon completion of this course the student will be able to:
1. Describe the two layers of the mucus blanket ( sol and gel layers) 2. Describe/identify the production, function and clearance of mucus in the health 3. Compare and contrast the mechanisms of action of Bland aerosols (hypertonic, isotonic, hypotonic) and mucolytic agents 4. Identify/describe the structure and composition of mucus 5. List factors that impair ciliary activity 6. List factors that lead to dehydration and thick mucus 7. Describe/ identify how mucolytics alter mucus structure 8. State/identify how the following mucolytic agents work, their indications, drug dosages and hazards, generic and trade names of each. (n-Acetylcysteine and dornase alfa) 9. Identify how expectorants affect the amount and production of mucus 10. Identify common expectorants( guaifenesin, terpin hydrate, ammonium chloride and potassium iodine)discuss when cough suppressants should and should not be utilized 11. Identify the structure and function of Type I and Type II cells 12. Describe the role of surfactants and surfactant replacement agents 13. State/identify how the following surfactant replacement agents work, their indications, drug dosages and hazards, generic and trade names of each.(calfactatn, beractant, poracant alfa) 14. Identify two therapeutic approaches to surfactant administration 15. Describe the administration of surfactant 16. Describe/identify positive and negative effects of surfactant replacement therapy The Anti-inflammatory and antiasthmatic agents
Upon completion of this course the student will be able to:
1. Describe/identify the inflammatory process as it realtes to airway disease 2. List/describe the chemical mediators involved in allergic reaction 3. Discuss/ describe/identify the physiology of corticosteroids 4. Identify/list common antigens RSPT 1113
Course Syllabi
Spring 2010
5. Identify common corticosteroids ( hydrocortisone, cortisone, prednisone, prednisolone, methylprednisolone, dexamethasone 6. Identify common inhaled corticosteroids/ side effects / dosage and trade and generic names of (beclomethosone, budesonide, flunisolide, fluticasone, mometasone, triamcinolone acetonide) 7. Identify benefits of inhaled steroids vs systemic 8. State the rational for the “mouth swish” post inhaled corticosteroid delivery 9. Discuss the actions of cromolyn and nedcromil sodium 10. State/identify how cromolyn and nedcromil sodium agents work, their indications, drug dosages and hazards, names of each. 11. List factors that influence mediator release for mast cells 12. Discuss/identify/discuss the pulmonary and systemic effects of histamine 13. List common antihistamines 14. State/identify common leukotriene modifiers/actions of work, their indications, drug dosages and hazards, names of each. Infectious Respiratory Disease
Upon completion of this course the student will be able to:
1. Describe the role of antimicrobial agents (antiviral, antibiotics and antiprotozal, 2. Match common antimicrobial agents to specific pathogens 3. State the difference between bactericidal and bacteriostatic 4. Explain the difference between broad-spectrum and narrow spectrum Cardiac agents
Upon completion of this course the student will be able to:
1. Describe indications and pharmacologic effects of antiarrhythmics, ACE inhibitors, angiotensin-receptor blockers, inotropic agents, antidiabetic agents, antilipidemics and vasodilators 2. List common drugs to treat heart failure and the effects of each 3. List common drugs used to treat Angina 4. List common drugs used to treat metabolic syndrome 5. List common drugs used to treat hypertension and hypotension 6. Describe and list indications and effects of anticoagulants, antiplatelets and Neuromuscular agents
Upon completion of this course the student will be able to:
1. Apply the principles of never transmission to pharmacology of neuromuscular 2. Discuss the mechanisms of action of medications that are hypnotic, sedative. 3. Describe the mechanism and role of ventilator stimulants 4. Describe the difference between depolarizing and nondepolarizing agents. 5. Explain duration of action, situations in which these drugs are used. 6. Identify the following drugs as depolarizing or non-depolarizing/ give trade and generic names. (Succinylcholine, Pancuronium,Vercuronium,Attacurium,Mivacurium, Cisatracurium,Doxacurium) RSPT 1113
Course Syllabi
Spring 2010
7. Describe what procedures should take place prior to the administration of 8. Describe procedures to take during and while neuromuscular agents are being Medical gases
Upon completion of this course the student will be able to:
1. Identify common indications for oxygen, helium, carbon dioxide and nitric oxide 2. Describe effects (positive and negative) of oxygen, helium, carbon dioxide and 3. List hazards of oxygen, helium, carbon dioxide and nitric oxide therapy 4. Describe/ identify the monitoring and assessment of oxygen, helium, carbon Contact Information:
Instructor:
Telephone:
Office hours: Posted outside office. Additional times are available with

Source: http://www.lit.edu/depts/allied/Syllabi/Fall2010/RSPT%201113%20(Fall%202010).pdf

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