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160 TORBAY ROAD MARKHAM ONTARIO L3R 1G6 CANADA
DATE PREPARED: June 27, 2007 SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - - CODE #: TB0504 NAME: TETRACYCLINE HYDROCHLORIDE SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - - CAS #: 64-75-5 MF: C22H24N2O8 EC NO: 200-593-8 SYNONYMS ACHROMYCIN HYDROCHLORIDE * ALA TET * AMYCIN, HYDROCHLORIDE * ARTOMYCIN * BRISTACYCLINE * CANCYCLINE-250 * CEFRACYCLINE TABLETS * CHLORHYDRATE DE TETRACYCLINE (FRENCH) * CHLOROWODORKU TETRACYKLINY (POLISH) * CYCLOPAR * DIACYCINE * DUMOCYCLIN * HOSTACYCLINE * MEDAMYCIN * MEPHACYCLIN * NCI-C55561 * NEOCYCLINE B * PALTET * PANMYCIN HYDROCHLORIDE * PARTREX * PIRACAPS * POLYCYCLINE HYDROCHLORIDE * POLYOTIC OINTMENT * QIDTET * QUADRACYCLINE * QUATREX * REMICYCLIN * RICYCLINE * RO-CYCLINE * SANCLOMYCINE * SANCLOMYCINE * STECLIN * STILCICLINA * SUBAMYCIN * SUMYCIN * SUPRAMYCIN * TEFILIN * TELINE * TELOTREX * TET-CY * TETRABAKAT * TETRABID * TETRABLET * TETRACAPS * TETRACHEL * TETRACICLINA CLORIDRATO (ITALIAN) * TETRACOMPREN * TETRACYCLINE CHLOROHYDRATE * TETRACYCLINE HYDROCHLORIDE * TETRA-D * TETRAKAP * TETRALUTION * TETRAMAVAN * TETRA- WEDEL * TETROSOL * TOPICYCLINE * TRIPHACYCLIN * U-5965 * UNICIN * UNIMYCIN * VETQUAMYCIN-324 * SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - - LABEL PRECAUTIONARY STATEMENTS TOXIC POSSIBLE RISK OF HARM TO THE UNBORN CHILD. MAY CAUSE SENSITIZATION BY INHALATION AND SKIN CONTACT. MAY CAUSE HARM TO BREASTFED BABIES. IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN. DANGER OF CUMULATIVE EFFECTS. CALIF. PROP. 65 REPRODUCTIVE HAZARD. TARGET ORGAN(S): LIVER TEETH IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
WEAR SUITABLE PROTECTIVE CLOTHING. DO NOT BREATHE DUST. SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - - IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS. CALL A PHYSICIAN. IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. IN CASE OF CONTACT, IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS AMOUNTS OF WATER. IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - - EXTINGUISHING MEDIA NONCOMBUSTIBLE. USE EXTINGUISHING MEDIA APPROPRIATE TO SURROUNDING FIRE CONDITIONS. SPECIAL FIREFIGHTING PROCEDURES WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO PREVENT CONTACT WITH SKIN AND EYES. UNUSUAL FIRE AND EXPLOSIONS HAZARDS EMITS TOXIC FUMES UNDER FIRE CONDITIONS. SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - - WEAR RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST. VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE. SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - - REFER TO SECTION 8. SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - - WASH THOROUGHLY AFTER HANDLING. DO NOT BREATHE DUST. AVOID CONTACT WITH EYES, SKIN AND CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE. NIOSH/MSHA-APPROVED RESPIRATOR. COMPATIBLE CHEMICAL-RESISTANT GLOVES. CHEMICAL SAFETY GOGGLES. SAFETY SHOWER AND EYE BATH. USE ONLY IN A CHEMICAL FUME HOOD. KEEP TIGHTLY CLOSED. STORE BELOW 0 C LIGHT SENSITIVE SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - - APPEARANCE AND ODOR SOLID. PHYSICAL PROPERTIES MELTING POINT: 220 - 223 C SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - - STABILITY STABLE.
CONDITIONS TO AVOID MAY DISCOLOR ON EXPOSURE TO LIGHT. INCOMPATIBILITIES STRONG OXIDIZING AGENTS HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS CARBON MONOXIDE, CARBON DIOXIDE NITROGEN OXIDES HYDROGEN CHLORIDE GAS HAZARDOUS POLYMERIZATION WILL NOT OCCUR. SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - - ACUTE EFFECTS CAUSES SKIN IRRITATION. MAY BE HARMFUL IF ABSORBED THROUGH THE SKIN. CAUSES EYE IRRITATION. MAY BE HARMFUL IF INHALED. MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER RESPIRATORY TRACT. MAY BE HARMFUL IF SWALLOWED. PROLONGED OR REPEATED EXPOSURE MAY CAUSE ALLERGIC REACTIONS IN CERTAIN SENSITIVE INDIVIDUALS. EXPOSURE CAN CAUSE: NAUSEA, VOMITING, DIARRHEA TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED. CHRONIC EFFECTS POSSIBLE RISK OF CONGENITAL MALFORMATION IN THE FETUS. TARGET ORGAN(S): LIVER TEETH BONES RTECS #: QI9100000 2-NAPHTHACENECARBOXAMIDE, 4-(DIMETHYLAMINO)-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-3,6,10,12,12A- PENTAHYDROXY-6-METHYL-1,11-DIOXO-, MONOHYDROCHLORIDE TOXICITY DATA ORL-RAT LD50:6443 MG/KG TXAPA9 18,185,1971 IPR-RAT LD50:318 MG/KG GNRIDX 2,26,1968 SCU-RAT LD50:700 MG/KG TXAPA9 9,445,1966 IVN-RAT LD50:128 MG/KG FRPSAX 10,197,1955 ORL-MUS LD50:2759 MG/KG JPPMAB 16,33,1964 IPR-MUS LD50:368 MG/KG JPPMAB 16,33,1964 IVN-MUS LD50:157 MG/KG FRPSAX 10,197,1955 UNR-MUS LD50:105 MG/KG 40YJAX -,55,1979 TARGET ORGAN DATA SENSE ORGANS AND SPECIAL SENSES (TASTE FUNCTION) LUNGS, THORAX OR RESPIRATION (FIBROSIS, INTERSTITIAL) LUNGS, THORAX OR RESPIRATION (OTHER CHANGES) GASTROINTESTINAL (HYPERMOTILITY, DIARRHEA) MATERNAL EFFECTS (UTERUS, CERVIX, VAGINA) EFFECTS ON FERTILITY (POST-IMPLANTATION MORTALITY) EFFECTS ON FERTILITY (ABORTION) EFFECTS ON EMBRYO OR FETUS (EXTRA EMBRYONIC STRUCTURES) EFFECTS ON EMBRYO OR FETUS (FETOTOXICITY) EFFECTS ON EMBRYO OR FETUS (FETAL DEATH)
EFFECTS ON EMBRYO OR FETUS (OTHER EFFECTS TO EMBYRO OR FETUS) SPECIFIC DEVELOPMENTAL ABNORMALITIES (MUSCULOSKELETAL SYSTEM) ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPLETE INFORMATION. SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - - DATA NOT YET AVAILABLE. SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - - CONTACT A LICENSED PROFESSIONAL WASTE DISPOSAL SERVICE TO DISPOSE OF THIS MATERIAL. DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS. SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - - NOT REGULATED. SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - - EUROPEAN INFORMATION R 60/61 MAY IMPAIR FERTILITY, MAY CAUSE HARM TO THE UNBORN CHILD. R 23/24/25 TOXIC BY INHALATION IN CONTACT WITH SKIN AND IF SWALLOWED. R 42/43 MAY CAUSE SENSITIZATION BY INHALATION. MAY CAUSE SENSITIZATION BY SKIN CONTACT. R 36/37/38 IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN. S 36/37/39 WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE PROTECTION. REVIEWS, STANDARDS, AND REGULATIONS OEL=MAK NOHS 1974: HZD 83550; NIS 2; TNF 474; NOS 2; TNE 1795 NOES 1983: HZD 83550; NIS 4; TNF 680; NOS 15; TNE 22901; TFE 17276 EPA TSCA SECTION 8(B) CHEMICAL INVENTORY NTP CARCINOGENESIS STUDIES (FEED);NO EVIDENCE:MOUSE,RAT NTPTR* NTP-TR-363,1989 U.S. INFORMATION THIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING REQUIREMENTS. THIS PRODUCT IS OR CONTAINS CHEMICAL(S) KNOWN TO THE STATE OF CALIFORNIA TO CAUSE DEVELOPMENTAL TOXICITY. SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - - THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. BIO BASIC INC. SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
Summer 2003 EPI NEWS VOL. 3 NO. 3 A Publication of the Genesee County Health Department West Nile Virus Update WNV cases have been reported from Genesee County. The majority of human WNV cases this W the Middle East. It is a close relative year continue to arise from the Central U.S. of the St. Louis encephalitis virus and can infect Experts now believe that WNV will appea
nearby. Less often, a person might get the flu by touching something that has flu virus on it and then touching their own mouth, eyes or nose. What are the symptoms of flu? Symptoms of flu can include fever, cough, sore throat, runny or stuffy nose, body aches, head- ache, chills, fatigue and sometimes vomiting and diarrhea. Some people with flu will not have a fever. How long can a si