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Cobre.pbrc.edu

Publications by Researchers Using COBRE Funded Core Facilities
(As of 10/31/2012)
Zhang J, Wang Y, Gao Z, Yun Z, Ye J. Hypoxia-inducible factor 1 activation from adipose protein 2-cre mediated knockout of von hippel-lindau gene leads to embryonic lethality. Clin Exp Pharmacol Physiol. 2012;39(2):145-50. PMCID: 3269514. Xu F, Burk D, Gao Z, Yin J, Zhang X, Weng J, et al. Angiogenic deficiency and adipose tissue dysfunction are associated with macrophage malfunction in SIRT1-/- mice. Endocrinology. 2012;153(4):1706-16. PMCID: 3320251. Williamson DA, Champagne CM, Harsha DW, Han H, Martin CK, Newton RL, Jr., et al. Effect of an environmental school-based obesity prevention program on changes in body fat and body weight: a randomized trial. Obesity (Silver Spring). 2012;20(8):1653-61. PMCID: 3374922. Wang ZQ, Yu Y, Zhang XH, Qin J, Floyd E. Gene expression profile in human skeletal muscle cells infected with human adenovirus type 36. J Med Virol. 2012;84(8):1254-66. Tchoukalova YD, Fitch M, Rogers PM, Covington JD, Henagan TM, Ye J, et al. In vivo adipogenesis in rats measured by cell kinetics in adipocytes and plastic-adherent stroma-vascular cells in response to high-fat diet and thiazolidinedione. Diabetes. 2012;61(1):137-44. PMCID: 3237665. Tam CS, Sparks LM, Johannsen DL, Covington JD, Church TS, Ravussin E. Low macrophage accumulation in skeletal muscle of obese type 2 diabetics and elderly subjects. Obesity (Silver Spring). 2012;20(7):1530-3. Sutton GM, Ptitsyn AA, Floyd ZE, Yu G, Wu X, Hamel K, et al. Biological aging alters circadian mechanisms in murine adipose tissue depots. Age (Dordr). 2012. Stull AJ, Wang ZQ, Zhang XH, Yu Y, Johnson WD, Cefalu WT. Skeletal muscle protein tyrosine phosphatase 1B regulates insulin sensitivity in African Americans. Diabetes. 2012;61(6):1415-22. PMCID: 3357297. Stavniichuk R, Shevalye H, Hirooka H, Nadler JL, Obrosova IG. Interplay of sorbitol pathway of glucose metabolism, 12/15-lipoxygenase, and mitogen-activated protein kinases in the pathogenesis of diabetic peripheral neuropathy. Biochem Pharmacol. 2012;83(7):932-40. PMCID: 3288510. Staszkiewicz J, Gimble JM, Dietrich MA, Gawronska-Kozak B. Diet-induced obesity in stem cell antigen-1 KO mice. Stem Cells Dev. 2012;21(2):249-59. PMCID: 3258438. Shevalye H, Lupachyk S, Watcho P, Stavniichuk R, Khazim K, Abboud HE, et al. Prediabetic nephropathy as an early consequence of the high-calorie/high-fat diet: relation to oxidative stress. Endocrinology. 2012;153(3):1152-61. PMCID: 3281531. Qiu G, Spangler EL, Wan R, Miller M, Mattson MP, So KF, et al. Neuroprotection provided by dietary restriction in rats is further enhanced by reducing glucocortocoids. Neurobiol Aging. 2012;33(10):2398-410. PMCID: 3374050. Purpera MN, Shen L, Taghavi M, Munzberg H, Martin RJ, Hutson SM, et al. Impaired branched chain amino acid metabolism alters feeding behavior and increases orexigenic neuropeptide expression in the hypothalamus. J Endocrinol. 2012;212(1):85-94. PMCID: 3350378. Pistell PJ, Spangler EL, Kelly-Bell B, Miller MG, de Cabo R, Ingram DK. Age-associated learning and memory deficits in two mouse versions of the stone T-maze. Neurobiol Aging. 2012;33(10):2431-9. PMCID: 3321391. Muoio DM, Noland RC, Kovalik JP, Seiler SE, Davies MN, DeBalsi KL, et al. Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility. Cell Metab. 2012;15(5):764-77. PMCID: 3348515. Martin CK, Correa JB, Han H, Allen HR, Rood JC, Champagne CM, et al. Validity of the Remote Food Photography Method (RFPM) for estimating energy and nutrient intake in near real-time. Obesity (Silver Spring). 2012;20(4):891-9. Lupachyk S, Stavniichuk R, Komissarenko JI, Drel VR, Obrosov AA, El-Remessy AB, et al. Na+/H+-exchanger-1 inhibition counteracts diabetic cataract formation and retinal oxidative-nitrative stress and apoptosis. Int J Mol Med. 2012;29(6):989-98. PMCID: 3375174. Li H, Gao Z, Zhang J, Ye X, Xu A, Ye J, et al. Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3. Diabetes. 2012;61(4):797-806. PMCID: 3314370. Kozak LP, Koza RA, Anunciado-Koza R, Mendoza T, Newman S. Inherent plasticity of brown adipogenesis in white fat of mice allows for recovery from effects of post-natal malnutrition. PLoS One. 2012;7(2):e30392. PMCID: 3286483. Kilroy G, Kirk-Ballard H, Carter LE, Floyd ZE. The ubiquitin ligase Siah2 regulates PPARgamma activity in adipocytes. Endocrinology. 2012;153(3):1206-18. PMCID: 3281538. Katzmarzyk PT, Barreira TV, Harrington DM, Staiano AE, Heymsfield SB, Gimble JM. Relationship between abdominal fat and bone mineral density in white and African American adults. Bone. 2012;50(2):576-9. Johannsen DL, Conley KE, Bajpeyi S, Punyanitya M, Gallagher D, Zhang Z, et al. Ectopic lipid accumulation and reduced glucose tolerance in elderly adults are accompanied by altered skeletal muscle mitochondrial activity. J Clin Endocrinol Metab. 2012;97(1):242-50. PMCID: 3251940. Gupta S, Knight AG, Losso BY, Ingram DK, Keller JN, Bruce-Keller AJ. Brain injury caused by HIV protease inhibitors: role of lipodystrophy and insulin resistance. Antiviral Res. 2012;95(1):19-29. PMCID: 3400265. Ganesh Kumar K, Zhang J, Gao S, Rossi J, McGuinness OP, Halem HH, et al. Adropin deficiency is associated with increased adiposity and insulin resistance. Obesity (Silver Spring). 2012;20(7):1394-402. Galgani JE, Ravussin E. Postprandial whole-body glycolysis is similar in insulin-resistant and insulin-sensitive non-diabetic humans. Diabetologia. 2012;55(3):737-42. Coulon SM, Miller AC, Reed JM, Martin CK. Reliability of a common solution-based taste perception test: implications for validity and a briefer test. Eat Behav. 2012;13(1):42-5. PMCID: 3244673. Chang JS, Fernand V, Zhang Y, Shin J, Jun HJ, Joshi Y, et al. NT-PGC-1alpha protein is sufficient to link beta3-adrenergic receptor activation to transcriptional and physiological components of adaptive thermogenesis. J Biol Chem. 2012;287(12):9100-11. PMCID: 3308807. Carter LE, Kilroy G, Gimble JM, Floyd ZE. An improved method for isolation of RNA from bone. BMC Biotechnol. 2012;12:5. PMCID: 3282642. Bennett B, Larson-Meyer DE, Ravussin E, Volaufova J, Soros A, Cefalu WT, et al. Impaired insulin sensitivity and elevated ectopic fat in healthy obese vs. nonobese prepubertal children. Obesity (Silver Spring). 2012;20(2):371-5. Badin PM, Loubiere C, Coonen M, Louche K, Tavernier G, Bourlier V, et al. Regulation of skeletal muscle lipolysis and oxidative metabolism by the co-lipase CGI-58. J Lipid Res. 2012;53(5):839-48. PMCID: 3329383. Zhang Y, Kerman IA, Laque A, Nguyen P, Faouzi M, Louis GW, et al. Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits. J Neurosci. 2011;31(5):1873-84. PMCID: 3069639. Zhang J, Henagan TM, Gao Z, Ye J. Inhibition of glyceroneogenesis by histone deacetylase 3 contributes to lipodystrophy in mice with adipose tissue inflammation. Endocrinology. 2011;152(5):1829-38. PMCID: 3075929. Youm YH, Adijiang A, Vandanmagsar B, Burk D, Ravussin A, Dixit VD. Elimination of the NLRP3-ASC inflammasome protects against chronic obesity-induced pancreatic damage. Endocrinology. 2011;152(11):4039-45. PMCID: 3199005. Williamson DA, Han H, Johnson WD, Stewart TM, Harsha DW. Longitudinal study of body weight changes in children: who is gaining and who is losing weight. Obesity (Silver Spring). 2011;19(3):667-70. PMCID: 3026913. Wicks SE, Londot H, Zhang B, Dowden J, Klopf-Eiermann J, Fisher-Perkins JM, et al. Effect of intrastriatal mesenchymal stromal cell injection on progression of a murine model of Krabbe disease. Behav Brain Res. 2011;225(2):415-25. PMCID: 3179783. Watcho P, Stavniichuk R, Tane P, Shevalye H, Maksimchyk Y, Pacher P, et al. Evaluation of PMI-5011, an ethanolic extract of Artemisia dracunculus L., on peripheral neuropathy in streptozotocin-diabetic mice. Int J Mol Med. 2011;27(3):299-307. PMCID: 3044440. Wang ZQ, Ribnicky D, Zhang XH, Zuberi A, Raskin I, Yu Y, et al. An extract of Artemisia dracunculus L. enhances insulin receptor signaling and modulates gene expression in skeletal muscle in KK-A(y) mice. J Nutr Biochem. 2011;22(1):71-8. Vandanmagsar B, Youm YH, Ravussin A, Galgani JE, Stadler K, Mynatt RL, et al. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med. 2011;17(2):179-88. PMCID: 3076025. Twiner EM, Liu Z, Gimble J, Yu Y, Greenway F. Pharmacokinetic pilot study of the antiangiogenic activity of standardized platycodi radix. Adv Ther. 2011;28(10):857-65. Stewart T, Han H, Allen RH, Bathalon G, Ryan DH, Newton RL, Jr., et al. H.E.A.L.T.H.: efficacy of an internet/population-based behavioral weight management program for the U.S. Army. J Diabetes Sci Technol. 2011;5(1):178-87. PMCID: 3045224. Stavniichuk R, Drel VR, Shevalye H, Maksimchyk Y, Kuchmerovska TM, Nadler JL, et al. Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative-nitrosative stress and p38 MAPK activation. Exp Neurol. 2011;230(1):106-13. Sparks LM, Moro C, Ukropcova B, Bajpeyi S, Civitarese AE, Hulver MW, et al. Remodeling lipid metabolism and improving insulin responsiveness in human primary myotubes. PLoS One. 2011;6(7):e21068. PMCID: 3132732. Smith BJ, Sutton GM, Wu X, Yu G, Goh BC, Hebert T, et al. Ovariectomy and genes encoding core circadian regulatory proteins in murine bone. Osteoporos Int. 2011;22(5):1633-9. Siegel MP, Kruse SE, Knowels G, Salmon A, Beyer R, Xie H, et al. Reduced coupling of oxidative phosphorylation in vivo precedes electron transport chain defects due to mild oxidative stress in mice. PLoS One. 2011;6(11):e26963. PMCID: 3222658. Salbaum JM, Kruger C, Zhang X, Delahaye NA, Pavlinkova G, Burk DH, et al. Altered gene expression and spongiotrophoblast differentiation in placenta from a mouse model of diabetes in pregnancy. Diabetologia. 2011;54(7):1909-20. Ruggiero C, Ehrenshaft M, Cleland E, Stadler K. High-fat diet induces an initial adaptation of mitochondrial bioenergetics in the kidney despite evident oxidative stress and mitochondrial ROS production. Am J Physiol Endocrinol Metab. 2011;300(6):E1047-58. PMCID: 3118596. Redman LM, Moro C, Dobak J, Yu Y, Guillot TS, Greenway FL. Association of beta-2 adrenergic agonist and corticosteroid injection in the treatment of lipomas. Diabetes Obes Metab. 2011;13(6):517-22. Redman LM, Huffman KM, Landerman LR, Pieper CF, Bain JR, Muehlbauer MJ, et al. Effect of caloric restriction with and without exercise on metabolic intermediates in nonobese men and women. J Clin Endocrinol Metab. 2011;96(2):E312-21. PMCID: 3048325. Redman LM, Elkind-Hirsch K, Ravussin E. Aerobic exercise in women with polycystic ovary syndrome improves ovarian morphology independent of changes in body composition. Fertil Steril. 2011;95(8):2696-9. PMCID: 3115385. Ravussin E, Galgani JE. The implication of brown adipose tissue for humans. Primeaux SD. QRFP in female rats: effects on high fat food intake and hypothalamic gene expression across the estrous cycle. Peptides. 2011;32(6):1270-5. PMCID: 3109089. Plaisance EP, Greenway FL, Boudreau A, Hill KL, Johnson WD, Krajcik RA, et al. Dietary methionine restriction increases fat oxidation in obese adults with metabolic syndrome. J Clin Endocrinol Metab. 2011;96(5):E836-40. PMCID: 3085194. Pachon-Pena G, Yu G, Tucker A, Wu X, Vendrell J, Bunnell BA, et al. Stromal stem cells from adipose tissue and bone marrow of age-matched female donors display distinct immunophenotypic profiles. J Cell Physiol. 2011;226(3):843-51. Newton RL, Thomson JL, Rau KK, Ragusa SA, Sample AD, Singleton NN, et al. Psychometric characteristics of process evaluation measures for a rural school-based childhood obesity prevention study: Louisiana Health. Am J Health Promot. 2011;25(6):417-21. PMCID: 3132146. Newton RL, Jr., Han H, Stewart TM, Ryan DH, Williamson DA. Efficacy of a pilot Internet-based weight management program (H.E.A.L.T.H.) and longitudinal physical fitness data in Army Reserve soldiers. J Diabetes Sci Technol. 2011;5(5):1255-62. PMCID: 3208890. Newton RL, Han H, Sothern M, Martin CK, Webber LS, Williamson DA. Accelerometry measured ethnic differences in activity in rural adolescents. J Phys Act Health. 2011;8(2):287-95. PMCID: 3074436. McDougal DH, Hermann GE, Rogers RC. Vagal afferent stimulation activates astrocytes in the nucleus of the solitary tract via AMPA receptors: evidence of an atypical neural-glial interaction in the brainstem. J Neurosci. 2011;31(39):14037-45. Martin CK, Rosenbaum D, Han H, Geiselman PJ, Wyatt HR, Hill JO, et al. Change in food cravings, food preferences, and appetite during a low-carbohydrate and low-fat diet. Obesity (Silver Spring). 2011;19(10):1963-70. PMCID: 3139783. Martin CK, Das SK, Lindblad L, Racette SB, McCrory MA, Weiss EP, et al. Effect of calorie restriction on the free-living physical activity levels of nonobese humans: results of three randomized trials. J Appl Physiol. 2011;110(4):956-63. PMCID: 3075130. Lupachyk S, Shevalye H, Maksimchyk Y, Drel VR, Obrosova IG. PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: correlation with peripheral nerve function. Free Radic Biol Med. 2011;50(10):1400-9. PMCID: 3081984. Lee EK, Lee MJ, Abdelmohsen K, Kim W, Kim MM, Srikantan S, et al. miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression. Mol Cell Biol. 2011;31(4):626-38. PMCID: 3028659. Lecoultre V, Ravussin E, Redman LM. The fall in leptin concentration is a major determinant of the metabolic adaptation induced by caloric restriction independently of the changes in leptin circadian rhythms. J Clin Endocrinol Metab. 2011;96(9):E1512-6. PMCID: 3167663. Larson-Meyer DE, Newcomer BR, Ravussin E, Volaufova J, Bennett B, Chalew S, et al. Intrahepatic and intramyocellular lipids are determinants of insulin resistance in prepubertal children. Diabetologia. 2011;54(4):869-75. PMCID: 3053439. Krishnapuram R, Kirk-Ballard H, Zuberi A, Dhurandhar NV. Infectivity period of mice inoculated with human adenoviruses. Lab Anim. 2011;45(2):103-8. Krishnapuram R, Dhurandhar EJ, Dubuisson O, Kirk-Ballard H, Bajpeyi S, Butte N, et al. Template to improve glycemic control without reducing adiposity or dietary fat. Am J Physiol Endocrinol Metab. 2011;300(5):E779-89. PMCID: 3093976. Harris NR, Carter PR, Yadav AS, Watts MN, Zhang S, Kosloski-Davidson M, et al. Relationship between inflammation and tissue hypoxia in a mouse model of chronic colitis. Inflamm Bowel Dis. 2011;17(3):742-6. PMCID: 3013240. Galgani JE, Smith SR, Ravussin E. Assessment of EchoMRI-AH versus dual-energy X-ray absorptiometry to measure human body composition. Int J Obes (Lond). 2011;35(9):1241-6. PMCID: 3145037. Dubuisson O, Dhurandhar EJ, Krishnapuram R, Kirk-Ballard H, Gupta AK, Hegde V, et al. PPARgamma-independent increase in glucose uptake and adiponectin abundance in fat cells. Endocrinology. 2011;152(10):3648-60. PMCID: 3176641. Dhurandhar EJ, Dubuisson O, Mashtalir N, Krishnapuram R, Hegde V, Dhurandhar NV. E4orf1: a novel ligand that improves glucose disposal in cell culture. PLoS One. 2011;6(8):e23394. PMCID: 3160302. Caruso-Davis MK, Guillot TS, Podichetty VK, Mashtalir N, Dhurandhar NV, Dubuisson O, et al. Efficacy of low-level laser therapy for body contouring and spot fat reduction. Obes Surg. 2011;21(6):722-9. Bruce-Keller AJ, Gupta S, Knight AG, Beckett TL, McMullen JM, Davis PR, et al. Cognitive impairment in humanized APPxPS1 mice is linked to Abeta(1-42) and NOX activation. Neurobiol Dis. 2011;44(3):317-26. PMCID: 3185143. Begriche K, Sutton GM, Butler AA. Homeostastic and non-homeostatic functions of melanocortin-3 receptors in the control of energy balance and metabolism. Physiol Behav. 2011;104(4):546-54. PMCID: 3139773. Begriche K, Levasseur PR, Zhang J, Rossi J, Skorupa D, Solt LA, et al. Genetic dissection of the functions of the melanocortin-3 receptor, a seven-transmembrane G-protein-coupled receptor, suggests roles for central and peripheral receptors in energy homeostasis. J Biol Chem. 2011;286(47):40771-81. PMCID: 3220494. Barreira TV, Harrington DM, Staiano AE, Heymsfield SB, Katzmarzyk PT. Body adiposity index, body mass index, and body fat in white and black adults. Jama. 2011;306(8):828-30. Bajpeyi S, Pasarica M, Moro C, Conley K, Jubrias S, Sereda O, et al. Skeletal muscle mitochondrial capacity and insulin resistance in type 2 diabetes. J Clin Endocrinol Metab. 2011;96(4):1160-8. PMCID: 3070252. Aggarwal S, Ndinguri MW, Solipuram R, Wakamatsu N, Hammer RP, Ingram D, et al. [DLys(6)]-luteinizing hormone releasing hormone-curcumin conjugate inhibits pancreatic cancer cell growth in vitro and in vivo. Int J Cancer. 2011;129(7):1611-23. Abuznait AH, Cain C, Ingram D, Burk D, Kaddoumi A, editors. Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimer's disease. J Pharm Pharmacol; 2011 Aug3163078. Yu G, Wu X, Dietrich MA, Polk P, Scott LK, Ptitsyn AA, et al. Yield and characterization of subcutaneous human adipose-derived stem cells by flow cytometric and adipogenic mRNA analyzes. Cytotherapy. 2010;12(4):538-46. Youm YH, Yang H, Amin R, Smith SR, Leff T, Dixit VD. Thiazolidinedione treatment and constitutive-PPARgamma activation induces ectopic adipogenesis and promotes age-related thymic involution. Aging Cell. 2010;9(4):478-89. PMCID: 2910128. Yang H, Youm YH, Vandanmagsar B, Ravussin A, Gimble JM, Greenway F, et al. Obesity increases the production of proinflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: implications for systemic inflammation and insulin resistance. J Immunol. 2010;185(3):1836-45. Xu F, Gao Z, Zhang J, Rivera CA, Yin J, Weng J, et al. Lack of SIRT1 (Mammalian Sirtuin 1) activity leads to liver steatosis in the SIRT1+/- mice: a role of lipid mobilization and inflammation. Endocrinology. 2010;151(6):2504-14. PMCID: 2875813. White CL, Purpera MN, Ballard K, Morrison CD. Decreased food intake following overfeeding involves leptin-dependent and leptin-independent mechanisms. Physiol Behav. 2010;100(4):408-16. PMCID: 2875678. Wang ZQ, Yu Y, Zhang XH, Floyd EZ, Cefalu WT. Human adenovirus 36 decreases fatty acid oxidation and increases de novo lipogenesis in primary cultured human skeletal muscle cells by promoting Cidec/FSP27 expression. Int J Obes (Lond). 2010;34(9):1355-64. Wang ZQ, Yu, Y., Zhang, Z.H., Floyd, Z.E., Cefalu, W.T. Adenovirus 36 decreases fatty acid oxidation and incrases de novo kipogenesis in primary cultured human skeletal muscle cells by promoting Cidec/FSP27 Expression. Int J Obes. 2010;10. Tompkins CL, Cefalu W, Ravussin E, Goran M, Soros A, Volaufova J, et al. Feasibility of intravenous glucose tolerance testing prior to puberty. Int J Pediatr Obes. 2010;5(1):51-5. Thirumala S, Gimble JM, Devireddy RV. Evaluation of methylcellulose and dimethyl sulfoxide as the cryoprotectants in a serum-free freezing media for cryopreservation of adipose-derived adult stem cells. Stem Cells Dev. 2010;19(4):513-22. PMCID: 3139530. Thirumala S, Gimble JM, Devireddy RV. Cryopreservation of stromal vascular fraction of adipose tissue in a serum-free freezing medium. J Tissue Eng Regen Med. 2010;4(3):224-32. Tang T, Zhang J, Yin J, Staszkiewicz J, Gawronska-Kozak B, Jung DY, et al. Uncoupling of inflammation and insulin resistance by NF-kappaB in transgenic mice through elevated energy expenditure. J Biol Chem. 2010;285(7):4637-44. PMCID: 2836069. Sutton GM, Centanni AV, Butler AA. Protein malnutrition during pregnancy in C57BL/6J mice results in offspring with altered circadian physiology before obesity. Endocrinology. 2010;151(4):1570-80. PMCID: 2850243. Sutton GM, Begriche K, Kumar KG, Gimble JM, Perez-Tilve D, Nogueiras R, et al. Central nervous system melanocortin-3 receptors are required for synchronizing metabolism during entrainment to restricted feeding during the light cycle. Faseb J. 2010;24(3):862-72. PMCID: 2830138. Stull AJ, Galgani JE, Johnson WD, Cefalu WT. The contribution of race and diabetes status to metabolic flexibility in humans. Metabolism. 2010;59(9):1358-64. Stull AJ, Cash KC, Johnson WD, Champagne CM, Cefalu WT. Bioactives in blueberries improve insulin sensitivity in obese, insulin-resistant men and women. J Nutr. 2010;140(10):1764-8. PMCID: 3139238. Stavniichuk R, Drel VR, Shevalye H, Vareniuk I, Stevens MJ, Nadler JL, et al. Role of 12/15-lipoxygenase in nitrosative stress and peripheral prediabetic and diabetic neuropathies. Free Radic Biol Med. 2010;49(6):1036-45. PMCID: 3056543. Staszkiewicz J, Frazier TP, Rowan BG, Bunnell BA, Chiu ES, Gimble JM, et al. Cell growth characteristics, differentiation frequency, and immunophenotype of adult ear mesenchymal stem cells. Stem Cells Dev. 2010;19(1):83-92. PMCID: 3136722. Shevalye H, Maksimchyk Y, Watcho P, Obrosova IG. Poly(ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease. Biochim Biophys Acta. 2010;1802(11):1020-7. Redman LM, Veldhuis JD, Rood J, Smith SR, Williamson D, Ravussin E. The effect of caloric restriction interventions on growth hormone secretion in nonobese men and women. Aging Cell. 2010;9(1):32-9. PMCID: 2807912. Redman LM, Ravussin E. Lorcaserin for the treatment of obesity. Drugs Today Qualls-Creekmore E, Tong M, Holmes GM. Time-course of recovery of gastric emptying and motility in rats with experimental spinal cord injury. Neurogastroenterol Motil. 2010;22(1):62-9, e27-8. PMCID: 2805043. Primeaux SD, Barnes MJ, Braymer HD, Bray GA. Sensitivity to the satiating effects of exendin 4 is decreased in obesity-prone Osborne-Mendel rats compared to obesity-resistant S5B/Pl rats. Int J Obes (Lond). 2010;34(9):1427-33. PMCID: 2910155. 100. Plaisance EP, Henagan TM, Echlin H, Boudreau A, Hill KL, Lenard NR, et al. Role of beta-adrenergic receptors in the hyperphagic and hypermetabolic responses to dietary methionine restriction. Am J Physiol Regul Integr Comp Physiol. 2010;299(3):R740-50. PMCID: 2944424. 101. Pistell PJ, Morrison CD, Gupta S, Knight AG, Keller JN, Ingram DK, et al. Cognitive impairment following high fat diet consumption is associated with brain inflammation. J Neuroimmunol. 2010;219(1-2):25-32. PMCID: 2823983. 102. Pistell PJ, Gupta S, Knight AG, Domingue M, Uranga RM, Ingram DK, et al. Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice. Antiviral Res. 2010;88(3):334-42. PMCID: 2991583. 103. Pasarica M, Rood J, Ravussin E, Schwarz JM, Smith SR, Redman LM. Reduced oxygenation in human obese adipose tissue is associated with impaired insulin suppression of lipolysis. J Clin Endocrinol Metab. 2010;95(8):4052-5. PMCID: 2913036. 104. Obrosova IG, Stavniichuk R, Drel VR, Shevalye H, Vareniuk I, Nadler JL, et al. Different roles of 12/15-lipoxygenase in diabetic large and small fiber peripheral and autonomic neuropathies. Am J Pathol. 2010;177(3):1436-47. PMCID: 2928975. 105. Morrison CD, Pistell PJ, Ingram DK, Johnson WD, Liu Y, Fernandez-Kim SO, et al. High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling. J Neurochem. 2010;114(6):1581-9. PMCID: 2945419. 106. Mikkelsen TS, Xu Z, Zhang X, Wang L, Gimble JM, Lander ES, et al. Comparative epigenomic analysis of murine and human adipogenesis. Cell. 2010;143(1):156-69. PMCID: 2950833. 107. Martin CK, Thomson JL, LeBlanc MM, Stewart TM, Newton RL, Jr., Han H, et al. Children in school cafeterias select foods containing more saturated fat and energy than the Institute of Medicine recommendations. J Nutr. 2010;140(9):1653-60. PMCID: 2924597. 108. Larson-Meyer DE, Newcomer BR, VanVrancken-Tompkins CL, Sothern M. Feasibility of assessing liver lipid by proton magnetic resonance spectroscopy in healthy normal and overweight prepubertal children. Diabetes Technol Ther. 2010;12(3):207-12. PMCID: 2936257. 109. Kumar KG, DiCarlo LM, Volaufova J, Zuberi AR, Richards BK. Increased physical activity cosegregates with higher intake of carbohydrate and total calories in a subcongenic mouse strain. Mamm Genome. 2010;21(1-2):52-63. PMCID: 2904081. 110. Kozak LP, Newman S, Chao PM, Mendoza T, Koza RA. The early nutritional environment of mice determines the capacity for adipose tissue expansion by modulating genes of caveolae structure. PLoS One. 2010;5(6):e11015. PMCID: 2888576. 111. Hasek BE, Stewart LK, Henagan TM, Boudreau A, Lenard NR, Black C, et al. Dietary methionine restriction enhances metabolic flexibility and increases uncoupled respiration in both fed and fasted states. Am J Physiol Regul Integr Comp Physiol. 2010;299(3):R728-39. PMCID: 2944433. 112. Gupta AK, Bray GA, Greenway FL, Martin CK, Johnson WD, Smith SR. Pioglitazone, but not metformin, reduces liver fat in Type-2 diabetes mellitus independent of weight changes. J Diabetes Complications. 2010;24(5):289-96. PMCID: 2891296. 113. Galgani JE, Ryan DH, Ravussin E. Effect of capsinoids on energy metabolism in human subjects. Br J Nutr. 2010;103(1):38-42. 114. Galgani JE, Ravussin E. Effect of dihydrocapsiate on resting metabolic rate in humans. Am J Clin Nutr. 2010;92(5):1089-93. PMCID: 2954444. 115. Galgani JE, de Jonge L, Rood JC, Smith SR, Young AA, Ravussin E. Urinary C-peptide excretion: a novel alternate measure of insulin sensitivity in physiological conditions. Obesity (Silver Spring). 2010;18(9):1852-7. 116. Galgani JE, de Jonge L, Most MM, Bray GA, Smith SR. Effect of a 3-day high-fat feeding period on carbohydrate balance and ad libitum energy intake in humans. 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